Nutrition Evidence Alert – May 2024 – Longevity & Healthy Aging

From our Experts

From our Experts 

Vegetarian dietary patterns and mortality in Adventist Health Study 2 in JAMA Internal Medicine. 2013. With Expert Review from Karin Elgar 

Whey Protein Supplementation with or without Vitamin D on Sarcopenia-Related Measures: A Systematic Review and Meta-Analysis in Advances in Nutrition (Bethesda, Md.). 2023. With Expert Review from Miranda Harris 

Effects of whey and soy protein supplementation on inflammatory cytokines in older adults: a systematic review and meta-analysis in The British Journal of Nutrition. 2023. With Expert Review from Miranda Harris 

Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE study in Aging Cell. 2023. With Expert Review from Chloe Steele 

Polyphenol supplementation and executive functioning in overweight and obese adults at risk of cognitive impairment: A systematic review and meta-analysis in PloS One. 2023. With Expert Review from Ana-Paula Agrela 

Combined Red Clover isoflavones and probiotics potently reduce menopausal vasomotor symptoms in PloS One. 2017. With Expert Review from Clare Grundel 

We continue our 3 month focus on health and ageing with a look at the science on longevity. This was the theme of the keynote presentation from NED Editor-in-Chief Justin Roberts, at our inaugural NED Science Forum held at the Royal Society of Medicine on 13 May 2024. Much of the science Justin referenced in his talk is already on NED and some of it is enhanced with expert reviews and functional categorisation. If you are a BANT member, you can access a recording of the event from the website. We are working on the video editing now so watch out for announcements. 

In case you missed our wrap up of our Microbiome and Gut Health in the latest NED Journal, you can read it here. 

This NED Alert comes with support from Herrens Mark. 


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New NED Infobite! 

Every month, the NED Board selects key new research articles and creates a NED Infobite on the chosen theme. NED Infobites are great ways to swiftly upgrade your knowledge and for sharing with your followers. You can read the latest one on Nutrition and Longevity here. To scan the NED Infobite library, click here. 


Recommended Podcast this Month 

The Secret to a Long and Happy Life with Dan Buettner – from the Feel Better; Live More Podcast from Dr Rangan Chatterjee 


Your Reference Library 

For practitioners, researchers, policy makers and students with particular interest in this area, here’s our long list:

Dietary Interventions 

Life expectancy can increase by up to 10 years following sustained shifts towards healthier diets in the United Kingdomin Nature Food. 2023  

Muscle Mass Changes After Daily Consumption of Protein Mix Supplemented With Vitamin D in Adults Over 50 Years of Age: Subgroup Analysis According to the Serum 25(OH)D Levels of a Randomized Controlled Trial in Clinical Nutrition Research. 2023 

Associations between plant-based dietary patterns and risks of type 2 diabetes, cardiovascular disease, cancer, and mortality – a systematic review and meta-analysis in Nutrition Journal. 2023 

Effects of a Raisin Supplement on Cognitive Performance, Quality of Life, and Functional Activities in Healthy Older Adults-Randomized Clinical Trial in Nutrients. 2023 

Frailty-Preventing Effect of an Intervention Program Using a Novel Complete Nutritional “COMB-FP Meal”: A Pilot Randomized Control Trial in Nutrients. 2023 

Rationale of the association between Mediterranean diet and the risk of frailty in older adults and systematic review and meta-analysis in Experimental Gerontology. 2023 

Impact of a specialized oral nutritional supplement on quality of life in older adults following hospitalization: Post-hoc analysis of the NOURISH trial in Clinical Nutrition (Edinburgh, Scotland). 2023 

Are inflammatory markers associated with sarcopenia-related traits in older adults with sarcopenia? – A cross-sectional analysis of the ENHANce study in Experimental Gerontology. 2023 

Polyphenols and Ageing 

Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption in Proceedings of the National Academy of Sciences of the United States of America. 2023  

A Randomized, Double-Blind, Placebo-Controlled Study of an Anthocyanin-Rich Functional Ingredient on Cognitive Function and Eye Dryness in Late Adulthood Volunteers: Roles of Epigenetic and Gut Microbiome Modulations in Nutrients. 2023 

The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial in BMC Medicine. 2023 

Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption in Proceedings of the National Academy of Sciences of the United States of America. 2023 

Lifestyle, Education and Frailty 

Effects of an educational intervention on frailty status, physical function, physical activity, sleep patterns, and nutritional status of older adults with frailty or pre-frailty: the FRAGSALUD study in Frontiers in Public Health. 2023 

Individualized Hospital to Home, Exercise-Nutrition Self-Managed Intervention for Pre-Frail and Frail Hospitalized Older Adults: The INDEPENDENCE Randomized Controlled Pilot Trial in Clinical Interventions in Aging. 2023 

Effect of resistance training volume on body adiposity, metabolic risk, and inflammation in postmenopausal and older females: Systematic review and meta-analysis of randomized controlled trials in Journal of Sport and Health Science. 2023 

Physical Exercise and Dietary Supplementation in Middle-Aged and Older Women: A Systematic Review in Journal of Clinical Medicine. 2023 

The Influence of Whey Protein on Muscle Strength, Glycemic Control and Functional Tasks in Older Adults with Type 2 Diabetes Mellitus in a Resistance Exercise Program: Randomized and Triple Blind Clinical Trial in International Journal of Environmental Research and Public Health. 2023 

Effect of Supervised and Unsupervised Exercise Training in Outdoor Gym on the Lifestyle of Elderly People in International Journal of Environmental Research and Public Health. 2023 

The influence of vitamin D supplementation and strength training on health biomarkers and chromosomal damage in community-dwelling older adults in Redox Biology. 2023 

Effects of multi-domain intervention on intrinsic capacity in older adults: A systematic review of randomized controlled trials (RCTs) in Experimental Gerontology. 2023 

Cognitive Function in Ageing 

Improving Cognitive Function with Nutritional Supplements in Aging: A Comprehensive Narrative Review of Clinical Studies Investigating the Effects of Vitamins, Minerals, Antioxidants, and Other Dietary Supplements in Nutrients. 2023 

Cognitive stimulation and psychosocial results in older adults: A systematic review and meta-analysis in Archives of Gerontology and Geriatrics. 2023 

The effect of weight loss following 18 months of lifestyle intervention on brain age assessed with resting-state functional connectivity in eLife. 2023 

A multidomain intervention against cognitive decline in an at-risk-population in Germany: Results from the cluster-randomized trial in Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association. 2024 

Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons in The New England Journal of Medicine. 2023 

A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study in The American Journal of Clinical Nutrition. 2023 

Effect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised controlled trial in Nature Communications. 2024 

Effect of Calorie Restriction and Intermittent Fasting Regimens on Brain-Derived Neurotrophic Factor Levels and Cognitive Function in Humans: A Systematic Review in Medicina (Kaunas, Lithuania). 2024 




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Many of the studies have been reviewed by our dedicated Expert Review Panel to evaluate the clinical applications of recent research in a clinical setting.

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Download our Fact Sheets, designed to provide a simple overview of many common symptoms.

Our Fact Sheets provide an overview of many common health conditions and symptoms that can be supported with personalised nutrition and lifestyle interventions.

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Discover the BANT Food for your Health Toolbox

The BANT ‘Food for your Health’ toolbox of resources highlights the role of nutrition as prevention for poor health and diet-induced illness.

The toolbox is designed to encourage people to look at their diet with new eyes and to adopt a food-first approach as prevention for chronic disease.

Our free resources are designed to help distill nutritional science into practical client-friendly resources which educate on the importance of good nutrition, healthy food choices, and supportive lifestyle habits. More importantly, they help empower individuals to have greater autonomy over their health and wellbeing outcomes.

Discover a range of food & lifestyle guides, informative infographics, fact sheets and recipes here.

These resources provide a great introduction to nutrition and lifestyle considerations however, for more personalised recommendations, find a Registered Nutritional Therapy Practitioner here.


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