19 Jan 2024 Nutrition Evidence Alert – January 2024 – The Microbiome and its Many Associations with Health
From our Experts
Bifidobacterium longum subsp. longum Reduces Perceived Psychological Stress in Healthy Adults: An Exploratory Clinical Trial in Nutrients. 2023. With Expert Review from Ana-Paula Agrela
Early life gut microbiota profiles linked to synbiotic formula effects: a randomized clinical trial in European infants in The American Journal of Clinical Nutrition. 2023. With Expert Review from Wilma Kirsten
Comparative analysis of the efficacies of probiotic supplementation and glucose-lowering drugs for the treatment of type 2 diabetes: A systematic review and meta-analysis in Frontiers in Nutrition. 2022. With Expert Review from Kirsty Baxter
This month, we are kicking off a 3-month focus on the microbiome. This first alert, in what will become a microbiome series, aims to highlight the significant breadth of health implications of the microbiome. From different life stages, bodily systems and disease states, the science on the microbiome is building. Next month, we will focus on the microbiome and IBS and in March on microbiome/IBD associations.
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Podcasts Selected for you This Month
Stop Taking Probiotics (Maybe…) – Grace Kingswell in conversation with Alex Manos. State of Mind Podcast
Leveraging your microbiome for better skin, mood, and brain health, plus why most probiotics suck – Max Lugavere in conversation with Kiran Krishnan. The Genius Life Podcast
Your Reference Library
For practitioners, researchers, policy makers and students with particular interest in this area, here’s our long list
Early Life and the Microbiome:
Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial in Nature Communications. 2022
Early life gut microbiota profiles linked to synbiotic formula effects: a randomized clinical trial in European infants in The American Journal of Clinical Nutrition. 2023
Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants in Cell Host & Microbe. 2022
Effect of an Exclusive Human Milk Diet on the Gut Microbiome in Preterm Infants: A Randomized Clinical Trial in JAMA Network Open. 2023
Source of human milk (mother or donor) is more important than fortifier type (human or bovine) in shaping the preterm infant microbiome in Cell Reports. Medicine. 2022
Intestinal Microbial Composition of Children in a Randomized Controlled Trial of Probiotics to Treat Acute Gastroenteritis in Frontiers in Cellular and Infection Microbiology. 2022
Effect of Lacticaseibacillus paracasei N1115 on Immunomodulatory and Gut Microbial Composition in Young Children: A Randomized, Placebo-Controlled Study in Nutrients. 2023
Pre-diabetes/Type 2 Diabetes and the Microbiome:
High-fiber diet ameliorates gut microbiota, serum metabolism and emotional mood in type 2 diabetes patients in Frontiers in Cellular and Infection Microbiology. 2023
White common bean extract remodels the gut microbiota and ameliorates type 2 diabetes and its complications: A randomized double-blinded placebo-controlled trial in Frontiers in Endocrinology. 2022
Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study in Gut Microbes. 2022
Randomized controlled trial demonstrates response to a probiotic intervention for metabolic syndrome that may correspond to diet in Gut Microbes. 2023
The effects of probiotic and synbiotic supplementation on inflammation, oxidative stress, and circulating adiponectin and leptin concentration in subjects with prediabetes and type 2 diabetes mellitus: a GRADE-assessed systematic review, meta-analysis, and meta-regression of randomized clinical trials in European Journal of Nutrition. 2023
The Effect of Probiotic Supplements on Metabolic Parameters of People with Type 2 Diabetes in Greece-A Randomized, Double-Blind, Placebo-Controlled Study in Nutrients. 2023
The causal relationship between gut microbiota and type 2 diabetes: a two-sample Mendelian randomized study in Frontiers in Public Health. 2023
Impact of dietary interventions on pre-diabetic oral and gut microbiome, metabolites and cytokines in Nature Communications. 2023
Effects of Gut Microbiome Modulation on Reducing Adverse Health Outcomes among Elderly and Diabetes Patients during the COVID-19 Pandemic: A Randomised, Double-Blind, Placebo-Controlled Trial (IMPACT Study) in Nutrients. 2023
Non-alcoholic Fatty Liver Disease and the Microbiome:
Gut microbiota in nonalcoholic fatty liver disease: a PREDIMED-Plus trial sub analysis in Gut Microbes. 2023
A Low Glycemic Index Mediterranean Diet Combined with Aerobic Physical Activity Rearranges the Gut Microbiota Signature in NAFLD Patients in Nutrients. 2022
Overweight/Obesity and the Microbiome:
Effects of Synbiotic Supplementation on Metabolic Syndrome Traits and Gut Microbial Profile among Overweight and Obese Hong Kong Chinese Individuals: A Randomized Trial in Nutrients. 2023
Aspects of Aging and the Microbiome:
One-year supplementation with Lactobacillus reuteri ATCC PTA 6475 counteracts a degradation of gut microbiota in older women with low bone mineral density in NPJ Biofilms and Microbiomes. 2022
Effects of Lactiplantibacillus plantarum OLL2712 on Memory Function in Older Adults with Declining Memory: A Randomized Placebo-Controlled Trial in Nutrients. 2022
The effect of vitamin D supplementation on the gut microbiome in older Australians – Results from analyses of the D-Health Trial in Gut Microbes. 2023
Stress, Mood and the Microbiome:
Effects of Lactococcus lactis subsp. cremoris YRC3780 daily intake on the HPA axis response to acute psychological stress in healthy Japanese men in European Journal of Clinical Nutrition. 2022
Multispecies probiotic administration reduces emotional salience and improves mood in subjects with moderate depression: a randomised, double-blind, placebo-controlled study in Psychological Medicine. 2023
Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study in Nutrients. 2023
Food, Fibre, Pre- and Pro-biotics and the Microbiome:
Effect of ancient Khorasan wheat on gut microbiota, inflammation, and short-chain fatty acid production in patients with fibromyalgia in World Journal of Gastroenterology. 2022
Effect of synbiotic supplementation on immune parameters and gut microbiota in healthy adults: a double-blind randomized controlled trial in Gut Microbes. 2023
Walnut consumption and gut microbial metabolism: Results of an exploratory analysis from a randomized, crossover, controlled-feeding study in Clinical Nutrition (Edinburgh, Scotland). 2023
Interactions between Mediterranean Diet Supplemented with Dairy Foods and the Gut Microbiota Influence Cardiovascular Health in an Australian Population in Nutrients. 2023
Menopause and the Microbiome:
Effects of Lactobacillus gasseri CP2305 on Mild Menopausal Symptoms in Middle-Aged Women in Nutrients. 2022
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