Nutrition Evidence Alert – February 2024 – IBS & the Microbiome

From our Expert Panel

Efficacy of a Synbiotic Containing Lactobacillus paracasei DKGF1 and Opuntia humifusa in Elderly Patients with Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial in Gut and Liver. 2023. With Expert Review from Ana-Paula Agrela

Efficacy and dose response of Lactiplantibacillus plantarum in diarrhea-predominant irritable bowel syndrome in World Journal of Gastroenterology. 2023. With Expert Review from Chloe Steele

Effect of the probiotic strain, Lactiplantibacillus plantarum P9, on chronic constipation: A randomized, double-blind, placebo-controlled study in Pharmacological Research. 2023. With Expert Review from Kirsty Baxter

Low FODMAP diet reduces gastrointestinal symptoms in irritable bowel syndrome and clinical response could be predicted by symptom severity: A randomized crossover trial in Clinical Nutrition (Edinburgh, Scotland). 2022. With Expert Review from Kirsty Baxter

Predictors of Symptom-Specific Treatment Response to Dietary Interventions in Irritable Bowel Syndrome in Nutrients. 2022. With Expert Review from Wilma Kristen

Efficacy and Acceptability of Dietary Therapies in Non-Constipated Irritable Bowel Syndrome: A Randomized Trial of Traditional Dietary Advice, the Low FODMAP Diet, and the Gluten-Free Diet in Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 2022. With Expert Review from Karin Elgar

This month, we continue our focus on the microbiome, this time diving into the science on the diet, the microbiome and IBS.

Scroll for more nutrition and lifestyle science

Recommended Podcasts and Blogposts this Month

Dr Ruscio Radio – A Simple Probiotic Protocol to Improve IBS and Leaky Gut

Dr Ruscio Blog – What you should know about IBS and Probiotics

Optibac Probiotics Blog – The Best Probiotics for IBS Symptoms

Your Reference Library

For practitioners, researchers, policy makers and students with particular interest in this area, here’s our long list

Efficacy and Safety of the Adjuvant Use of Probiotic Bacillus clausii Strains in Pediatric Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study in Paediatric Drugs. 2023

An insight into the functional alterations in the gut microbiome of healthy adults in response to a multi-strain probiotic intake: a single arm open label trial in Frontiers in Cellular and Infection Microbiology. 2023

Blueberries Improve Abdominal Symptoms, Well-Being and Functioning in Patients with Functional Gastrointestinal Disorders in Nutrients. 2023

Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials in Frontiers in Immunology. 2023

Effects of FODMAPs and Gluten on Gut Microbiota and Their Association with the Metabolome in Irritable Bowel Syndrome: A Double-Blind, Randomized, Cross-Over Intervention Study in Nutrients. 2023

Efficacy of diet restriction with or without probiotic for treatment of patients with IBS-D: Phase I-II clinical trial in Immunity, Inflammation and Disease. 2023

The Effects of Agave Fructans in a Functional Food Consumed by Patients with Irritable Bowel Syndrome with Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial in Nutrients. 2023

Meta-analysis of the efficacy of probiotics to treat diarrhea in Medicine. 2022

Randomised controlled trial: effects of gluten-free diet on symptoms and the gut microenvironment in irritable bowel syndrome in Alimentary Pharmacology & Therapeutics. 2022

Fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial in The American Journal of Clinical Nutrition. 2022


Download our NED InfoBites for a snapshot of the latest science

Our scientific NED InfoBites are especially designed to provide you with our pick of the latest research in a handy one-page pdf, ideal for sharing with colleagues and clients.

Many of the studies have been reviewed by our dedicated Expert Review Panel to evaluate the clinical applications of recent research in a clinical setting.

Head over to our Youtube channel to listen to our Expert Reviewers discussing the science in NED Talks and browse our digital NED Journal.

Discover all available NED InfoBites here 

Download our Fact Sheets, designed to provide a simple overview of many common symptoms of IBS and Gut Disturbances.

Our Fact Sheets provide an overview of many common health conditions and symptoms that can be supported with personalised nutrition and lifestyle interventions.

Discover all available Fact Sheets here


Discover the BANT Food for your Health Toolbox

The BANT ‘Food for your Health’ toolbox of resources highlights the role of nutrition as prevention for poor health and diet-induced illness.

The toolbox is designed to encourage people to look at their diet with new eyes and to adopt a food-first approach as prevention for chronic disease.

Our free resources are designed to help distill nutritional science into practical client-friendly resources which educate on the importance of good nutrition, healthy food choices, and supportive lifestyle habits. More importantly, they help empower individuals to have greater autonomy over their health and wellbeing outcomes.

Discover a range of food & lifestyle guides, informative infographics, fact sheets and recipes here.

These resources provide a great introduction to nutrition and lifestyle considerations however, for more personalised recommendations, find a Registered Nutritional Therapy Practitioner here.



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