Nutrition Evidence Alert – April 2024 – Bone Health and Osteoporosis

From our Experts

This month sees the start of a 3 month focus on health and ageing. We begin with a look at our skeletons, focusing on fracture risk and osteoporosis. Next month, we will move to longevity and brain health, before concluding with novel food agents being trialled for longevity and health.

In case you missed our wrap up of our Microbiome and Gut Health in the latest NED Journal, you can read it here.

This NED Alert comes with support from Herrens Mark.

Additive Effects of Exercise and Vitamin D Supplementation (with and without Calcium) on Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis in Journal of Osteoporosis. 2023. With Expert Review from Chloe Steele

Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial in The American Journal of Clinical Nutrition. 2017. With Expert Review from Clare Grundel

The Effects of Polyphenols on Bone Metabolism in Postmenopausal Women: Systematic Review and Meta-Analysis of Randomized Control Trials in Antioxidants (Basel, Switzerland). 2023. With Expert Review from Chloe Steele

Evaluating adherence, tolerability and safety of oral calcium citrate in elderly osteopenic subjects: a real-life non-interventional, prospective, multicenter study in Aging Clinical and Experimental Research. 2024. With Expert Review from Ana-Paula Agrela

 

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Recommended Podcasts and Blogposts this Month

Bone Health: the impact of daily toxicant exposures – from the Institute of Functional Medicine blog

Connecting Bone and Gut Health – from the Institute of Functional Medicine blog

Podcast from Chris Kresser on How to Naturally Prevent and treat Osteopenia and Osteoporosis – Revolution Health Radio

Your Reference Library

For practitioners, researchers, policy makers and students with particular interest in this area, here’s our long list

The additive effect of vitamin K supplementation and bisphosphonate on fracture risk in post-menopausal osteoporosis: a randomised placebo controlled trial in Archives of Osteoporosis. 2023

Effect of a Hop Extract Standardized in 8-Prenylnaringenin on Bone Health and Gut Microbiome in Postmenopausal Women with Osteopenia: A One-Year Randomized, Double-Blind, Placebo-Controlled Trial in Nutrients. 2023

The Effects of Polyphenols on Bone Metabolism in Postmenopausal Women: Systematic Review and Meta-Analysis of Randomized Control Trials in Antioxidants (Basel, Switzerland). 2023

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial in Obesity (Silver Spring, Md.). 2023

One-year supplementation with Lactobacillus reuteri ATCC PTA 6475 counteracts a degradation of gut microbiota in older women with low bone mineral density in NPJ Biofilms and Microbiomes. 2022

Dietary Acid Load Was Positively Associated with the Risk of Hip Fracture in Elderly Adults in Nutrients. 2022

Meta-Analysis of Effects of Nutritional Intervention Combined with Calcium Carbonate D3 Tablets on Bone Mineral Density, Bone Metabolism, and Curative Effect in Patients with Osteoporosis in Contrast Media & Molecular Imaging. 2022

Vitamin D Boosts Alendronate Tail Effect on Bone Mineral Density in Postmenopausal Women with Osteoporosis in Nutrients. 2021

Association of Coffee and Tea Intake with Bone Mineral Density and Hip Fracture: A Meta-Analysis in Medicina (Kaunas, Lithuania). 2023

Reducing hip and non-vertebral fractures in institutionalised older adults by restoring inadequate intakes of protein and calcium is cost-saving in Age and Ageing. 2023

Effects of an 18-month community-based, multifaceted, exercise program on patient-reported outcomes in older adults at risk of fracture: secondary analysis of a randomised controlled trial in Osteoporosis International. 2023

Evaluating adherence, tolerability and safety of oral calcium citrate in elderly osteopenic subjects: a real-life non-interventional, prospective, multicenter study in Aging Clinical and Experimental Research. 2024

Meta-Analysis Reveals Compositional and Functional Microbial Changes Associated with Osteoporosis in Microbiology Spectrum. 2023

Does adding exercise or physical activity to pharmacological osteoporosis therapy in patients with increased fracture risk improve bone mineral density and lower fracture risk? A systematic review and meta-analysis in Osteoporosis International. 2023

A 2-yr Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health in Medicine and Science in Sports and Exercise. 2023

 

 

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These resources provide a great introduction to nutrition and lifestyle considerations however, for more personalised recommendations, find a Registered Nutritional Therapy Practitioner here.

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