Nutrition Evidence Alert – September 2025 – The Ketogenic Diet: What Science Says about Metabolising Fat for Fuel

From our Expert Review Panel

Very-low-calorie ketogenic diet vs hypocaloric balanced diet in the prevention of high-frequency episodic migraine: the EMIKETO randomized, controlled trial in The Journal of Nutrition and Healthy Ageing. 2024. With Expert Review from Karin Elgar

Effects of a Ketogenic Diet on Body Composition in Healthy, Young, Normal-Weight Women: A Randomized Controlled Feeding Trial in Nutrients. 2024. With Expert Review from Chloe Steele

Ketogenic Diet Induced Shifts in the Gut Microbiome Associate with Changes to Inflammatory Cytokines and Brain-Related miRNAs in Children with Autism Spectrum Disorder in Nutrients. 2024. With Expert Review from Wilma Kirsten

We are delighted to bring you the first NED Alert since the major upgrade, this month focusing on the science behind the ketogenic diet. Check out the expert reviews above and the reference list of articles below.

The next edition of the NED Journal will focus on Ketogenic Diets and the many different ways it is being tested in the research. Watch out too for our next NED article, on neurodivergence. 

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Happy reading!

 

New NED Infobite

Check out this new NED Infobite on the impacts of the ketogenic diet. With 4 new research articles examining how the ketogenic diet influences cognitive function in Alzheimer’s disease, improves insulin sensitivity and glycaemic control in type 2 diabetes, modulates inflammation relative to the Mediterranean diet in obesity and psoriasis, and alters body composition and strength.

For our full library of NED Infobites, see the orange Expert Opinion box on the database or grab them directly from BANT here.

 

Your Reference Library

Happy Reading! Please send comments and suggestions to [email protected]

Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT in Cell Reports Medicine. 2024.

The effect of the ketogenic diet on resistance training load management: a repeated-measures clinical trial in trained participants in Journal of the International Society of Sports Nutrition. 2024.

A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people with Parkinson’s disease in BMC Neurology. 2024.

Self-reported menses physiology is positively modulated by a well-formulated, energy-controlled ketogenic diet vs. low fat diet in women of reproductive age with overweight/obesity in PLoS one. 2024.

A 3-Week Ketogenic Diet Increases Skeletal Muscle Insulin Sensitivity in Individuals With Obesity: A Randomized Controlled Crossover Trial in Diabetes. 2024.

Addressing Pain Using a Mediterranean Ketogenic Nutrition Program in Older Adults with Mild Cognitive Impairment in Journal of pain research. 2024.

Effects of Different Exercises Combined with Different Dietary Interventions on Body Composition: A Systematic Review and Network Meta-Analysis in Nutrients. 2024.

Effect of weight-maintaining ketogenic diet on glycemic control and insulin sensitivity in obese T2D subjects in BMJ open diabetes research & care. 2024.

Asian Low-Carbohydrate Diet with Increased Whole Egg Consumption Improves Metabolic Outcomes in Metabolic Syndrome: A 52-Week Intervention Study in The Journal of nutrition. 2024.

Effects of ketogenic diet on weight loss parameters among obese or overweight patients with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trails in Food & nutrition research. 2024.

The effects of the ketogenic diet for the management of type 2 diabetes mellitus: A systematic review and meta-analysis of recent studies in Diabetes & metabolic syndrome. 2023.

Very-low-calorie ketogenic diet vs hypocaloric balanced diet in the prevention of high-frequency episodic migraine: the EMIKETO randomized, controlled trial in Journal of translational medicine. 2023.

If you are looking for further NED value-added research on nutrition and the ketogenic diet, you can find the full list here

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Access past NED InfoBites for a snapshot of the latest science

Our scientific NED InfoBites are especially designed to provide you with our pick of the latest research in a handy one-page pdf, ideal for sharing with colleagues and clients.

Many of the studies have been reviewed by our dedicated Expert Review Panel to evaluate the clinical applications of recent research in a clinical setting.

Head over to our Youtube channel to listen to our Expert Reviewers discussing the science in NED Talks and browse our digital NED Journal, a fantastic way to to take a deep dive into the science, with clinical implications and take aways relevant to your practice.

Discover all available NED InfoBites here 

 

Download our Symptomatology Fact Sheets, designed to provide a simple overview of common conditions.

BANT Fact Sheets provide commonly accepted overviews, symptoms and explanations of risk factors for a variety of non-communicable diseases that can be supported by personalised nutrition and lifestyle medicine. They are provided as free downloads enabling practitioners to utilise them in clinic and group settings.

Download them here.

 

Discover the BANT Food for your Health Toolbox

The BANT ‘Food for your Health’ toolbox of resources highlights the role of nutrition as prevention for poor health and diet-induced illness.

The toolbox is designed to encourage people to look at their diet with new eyes and to adopt a food-first approach as prevention for chronic disease.

Our free resources are designed to help distill nutritional science into practical client-friendly resources which educate on the importance of good nutrition, healthy food choices, and supportive lifestyle habits. More importantly, they help empower individuals to have greater autonomy over their health and wellbeing outcomes.

Discover a range of food & lifestyle guides, informative infographics, fact sheets and recipes here.

These resources provide a great introduction to nutrition and lifestyle considerations however, for more personalised recommendations, find a Registered Nutritional Therapy Practitioner here.

 

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