Nutrition Evidence Alert – November 2025 – Liver Health & Disease

From our Expert Review Panel

  • Severe Dietary Energy Restriction for Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomised Controlled Trial in Journal of Cachexia, Sarcopenia, and Muscle. 2025. With Expert Review from Karin Elgar
  • The efficacy of DASH combined with time-restricted feeding (168) on metabolic associated fatty liver disease management a randomized controlled trial in Scientific Reports. 2025. With Expert Review from Sarah Cassar
  • The effects of intermittent fasting on antioxidant and inflammatory markers and liver enzymes in postmenopausal, overweight and obese women with rheumatoid arthritis: a randomized controlled trial in Scientific Reports. 2025. With Expert Review from Karin Elgar
  • Effects of a 12-Week Mediterranean-Type Time-Restricted Feeding Protocol in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomised Controlled Trial-The ‘CHRONO-NAFLD Project’ in Alimentary Pharmacology & Therapeutics. 2025. With Expert Review from Chloe Steele
  • High-Intensity Interval Training Reduces Liver Enzyme Levels and Improves MASLD-Related Biomarkers in Overweight/Obese Girls in Nutrients. 2025. With Expert Review from Sarah Cassar
  • Exploring the Potential of Oral Butyrate Supplementation in Metabolic Dysfunction-Associated Steatotic Liver Disease: Subgroup Insights from an Interventional Study in International Journal of Molecular Sciences. 2025. With Expert Review from Chloe Steele.

Over the past month, we have been focusing our attention on the latest nutrition and lifestyle science related to liver health. Our master organ, it is involved in metabolism, detoxification, digestion, energy regulation, nutrient storage – and more – so is worth some attention when it comes to daily management. Have a read of the expert reviews, use the resources below as a library for future reference and check out the new NED Infobites.

In case you missed it last month, have a read of the latest NED Feature Article from our panel of experts. Lead by NED Editorial Board member, Dr Kate Lawrence, this article is a review of nutrition and lifestyle related to neurodivergence. You can read all past NED Feature articles here.

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Happy reading!

 

New NED Feature Article

Check out this new NED Feature Article – a review of the evidence-based considerations for nutritional therapy and personalised lifestyle support in neurodivergence.
For our full library of NED Feature Articles browse through the NED Journals or grab them directly from BANT here.

 

 New NED Infobite

Check out our new NED Infobites on the Liver Health. With 4 new research articles on each examining how the gut microbiota and liver interact, and nutrition and lifestyle support for liver health.

For our full library of NED Infobites, see the orange Expert Opinion box on the database or grab them directly from BANT here.

 

Your Reference Library

Your Reference Library

Happy Reading! Please send comments and suggestions to [email protected]

 

The efficacy of DASH combined with time-restricted feeding (16/8) on metabolic associated fatty liver disease management: a randomized controlled trial in Scientific Reports. 2025.

The Impact of Dietary Interventions on Metabolic Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Comorbid Conditions, Including Obesity and Type 2 Diabetes in Nutrients. 2025.

Effect of synbiotics on the cardiovascular risk factors in patients with non-alcoholic fatty liver: a GRADE assessed systematic review and meta-analysis in BMC Gastroenterology. 2025.

Dietary inflammatory index and non-alcoholic fatty liver disease risk: a systematic review and meta-analysis of observational studies in Frontiers in Nutrition. 2025.

Evidence on the link between hypothyroidism and non-alcoholic fatty liver disease: an updated systematic review in BMC Endocrine Disorders. 2025.

Gut Microbiota and Liver Health: Meta-Analysis of -Containing Probiotics in NAFLD Management in International Journal of Molecular Sciences. 2025.

Effects of Mediterranean diet, exercise, and their combination on body composition and liver outcomes in metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis of randomized controlled trials in BMC Medicine. 2025.

Effects of reducing sedentary behavior on liver insulin sensitivity, liver fat content, and liver enzyme levels: a six-month randomized controlled trial in American Journal of Physiology, Endocrinology and Metabolism. 2025.

Healthy Lifestyle and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Study of the Efficacy of Fatty Liver Regression in Clinical and Translational Gastroenterology. 2025.

Exploring the Potential of Oral Butyrate Supplementation in Metabolic Dysfunction-Associated Steatotic Liver Disease: Subgroup Insights from an Interventional Study in International Journal of Molecular Sciences. 2025.

Severe Dietary Energy Restriction for Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomised Controlled Trial in Journal of Cachexia, Sarcopenia, and Muscle. 2025.

The effects of intermittent fasting on antioxidant and inflammatory markers and liver enzymes in postmenopausal, overweight and obese women with rheumatoid arthritis: a randomized controlled trial in Scientific Reports. 2025.

Effects of a 12-Week Mediterranean-Type Time-Restricted Feeding Protocol in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomised Controlled Trial-The ‘CHRONO-NAFLD Project’ in Alimentary Pharmacology and Therapeutics. 2025.

Replacing dietary carbohydrate with protein and fat improves lipoprotein subclass profile and liver fat in type 2 diabetes independent of body weight: evidence from 2 randomized controlled trials in The American Journal of Clinical Nutrition. 2025.

High-Intensity Interval Training Reduces Liver Enzyme Levels and Improves MASLD-Related Biomarkers in Overweight/Obese Girls in Nutrients. 2025.

Vitamin E for people with non-alcoholic fatty liver disease in The Cochrane Database of Systematic Reviews. 2024.

Meta-analysis of probiotics efficacy in the treatment of minimum hepatic encephalopathy in Liver International: Official Journal of the International Association for the Study of the Liver. 2024.

Systematic review of exercise for the treatment of pediatric metabolic dysfunction-associated steatotic liver disease in PloS one. 2024.

Effect of a Low-Calorie Dietary Intervention on Liver Health and Body Weight in Adults with Metabolic-Dysfunction Associated Steatotic Liver Disease (MASLD) and Overweight/Obesity: A Systematic Review and Meta-Analysis in Nutrients. 2024.

No benefit of soluble fiber on liver function in International Journal for Vitamin and Nutrition Research. 2024.

S-Adenosylmethionine (SAMe) for Liver Health: A Systematic Review in Nutrients. 2024.


If you are looking for further NED value-added research on nutrition and liver, you can find the full list of expert reviews here

 

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Access past NED InfoBites for a snapshot of the latest science

Our scientific NED InfoBites are especially designed to provide you with our pick of the latest research in a handy one-page pdf, ideal for sharing with colleagues and clients.

Many of the studies have been reviewed by our dedicated Expert Review Panel to evaluate the clinical applications of recent research in a clinical setting.

Head over to our Youtube channel to listen to our Expert Reviewers discussing the science in NED Talks and browse our digital NED Journal, a fantastic way to to take a deep dive into the science, with clinical implications and take aways relevant to your practice.

Discover all available NED InfoBites here 

 

Download our Symptomatology Fact Sheets, designed to provide a simple overview of common conditions.

BANT Fact Sheets provide commonly accepted overviews, symptoms and explanations of risk factors for a variety of non-communicable diseases that can be supported by personalised nutrition and lifestyle medicine. They are provided as free downloads enabling practitioners to utilise them in clinic and group settings.

Download them here.

 

Discover the BANT Food for your Health Toolbox

The BANT ‘Food for your Health’ toolbox of resources highlights the role of nutrition as prevention for poor health and diet-induced illness.

The toolbox is designed to encourage people to look at their diet with new eyes and to adopt a food-first approach as prevention for chronic disease.

Our free resources are designed to help distill nutritional science into practical client-friendly resources which educate on the importance of good nutrition, healthy food choices, and supportive lifestyle habits. More importantly, they help empower individuals to have greater autonomy over their health and wellbeing outcomes.

Discover a range of food & lifestyle guides, informative infographics, fact sheets and recipes here.

These resources provide a great introduction to nutrition and lifestyle considerations however, for more personalised recommendations, find a Registered Nutritional Therapy Practitioner here.

 

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